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CAR T cancer therapy established in Saskatoon

Revolutionary immunotherapy now available for cancer patients in Saskatchewan.
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Health Minister Paul Merriman, seen here speaking at the Legislature, was at an event in Saskatoon launching new cancer treatment options in the province.

SASKATOON - Cancer patients in Saskatchewan now have an opportunity to receive some innovative life-saving treatment close to home.

It was announced Tuesday that the Saskatchewan Cancer Agency alongside Saskatchewan Health Authority has launched Chimeric Antigen Receptor T-cell (CAR T) therapy in Saskatoon.

This is immunotherapy used to treat adult cancer patients with certain blood cancers and lymphomas in the province. How it works is that the CAR T therapy program will collect a patient’s T- cells from their blood, then engineer them with genetic material to recognize and attack cancer cells. Those cells are then multiplied and infused back into the patient, which then go to work destroying the cancer cells.

This treatment is touted as giving hope to patients who are not responding to existing treatment or exhausted all other conventional treatment options. Involved in establishing the program has been the Saskatchewan Stem Cell Transplant and Cellular Therapy Program team at the Cancer Agency and the SHA, as well as partners in neurology, ICU and others.

According to a news release, the province has provided initial funding of $2.128M to develop the commercial CAR T program and is to provide around $6.7 million annually to operate the program and fund costs of treatment.

“We are pleased to now offer this revolutionary CAR T therapy in Saskatchewan, so that patients no longer need to travel out of province to take advantage of this potentially life- saving treatment,” said Saskatchewan Cancer Agency President and CEO Deb Bulych in a statement. “This exciting announcement would not be possible without the steadfast support from the Government of Saskatchewan, the Saskatchewan Health Authority and our health system partners.”

“Saskatchewan is now one of five provinces in Canada that has this new treatment option available to cancer patients closer to home,” Health Minister Paul Merriman said in a statement. “We are committed to providing Saskatchewan people with quick, convenient access to the highest quality care and new treatment options available.”

“Offering CAR T therapy availability in Saskatchewan allows patients to rapidly access treatment closer to home and provides better access to follow-up visits and ongoing support from their care team throughout the treatment process,” said Sharon Garratt, Saskatchewan Health Authority Vice President, in a statement. “The SHA is excited to provide our expertise to support this leading edge treatment.”

 

“This new therapy option is giving hope to some patients who are not responding to existing treatment or have already exhausted all other conventional treatment options available to them,” Saskatchewan Cancer Agency Hematologist, Dr. Mark Bosch said. “CAR T is still a relatively new process, but it is already showing promising results for patients around the world and right here in Saskatchewan, who have travelled elsewhere to receive the treatment.”

Saskatchewan patient, Gary Carriere, was diagnosed with lymphoma in March 2020. He underwent several rounds of chemotherapy and a stem cell transplant, which controlled his cancer for a short time, until it came back aggressively the following year. He traveled to Montreal alone in November 2022 to receive CAR T—the last treatment option available to him.

“It was very lonely and isolating to be far from home—in a different hospital and province—without my wife and family at my side while undergoing this new major procedure,” Carriere said. “It is such a relief to hear that future patients will not have to make that long, exhausting journey and can receive CAR T right here in our own backyard.

When you are facing a scary prognosis and this new therapy is your last real hope for recovery, being in a familiar place, surrounded by the people you love most, can make all the different in the world.”

Carriere is grateful to be now cancer-free thanks to the new CAR T therapy.

“Many of our patients express the same wish—to have more days to enjoy with their loved ones. This new treatment could help grant many more healthy days to some patients, and we can’t imagine a better gift than that precious time,” Bulych said.

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